Abstract.Patient-derived tumor organoids (PDOs) currently represent important modeling tools in pre-clinical investigation of malignancies.Organoid cultures conserve the genetic and phenotypic characteristics of the original tumor and maintain its heterogeneity, allowing their application Volleyballs in many research fields.PDOs derived from colore
Topography is a critical element in the hydrological response of a drainage basin and its availability in the form of digital elevation models (DEMs) has advanced the modeling of hydrological and hydraulic processes.However, progress experienced in these fields may stall, as intrinsic characteristics of free DEMs may limit new findings, while at th
Introduction.Preservation of historical and cultural environment is one of the most important tasks nowadays.Nevertheless, a developing city requires the development of architectural and urban environment, which contributes to the emerging of modern objects in historical areas of the city, often discordant.The primary parameter that determines the
Shiitake mushroom (Lentinula edodes (Berk.) Pegler) popular as both edible and medicinal, is one of the most cultivated and consumed mushroom species in the world.Cultivation of this mushroom on different agricultural wastes has been experimented in many studies until today.Nevertheless, agricultural waste Lamps trials are going on as agricultural
BACKGROUND:The genus Burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis.Drug resistance has made development of new antimicrobials critical.Many approaches Volleyballs to discovering new antimicrobials, such as structure-based drug design and